Inactivation of PPAR β / δ adversely affects satellite cells and reduces postnatal 1 myogenesis
نویسندگان
چکیده
School of Biological Sciences, Nanyang Technological University, Singapore 637551. 7 Singapore Institute for Clinical Sciences, Agency for Science, Technology and Research 8 (A*STAR), Brenner Centre for Molecular Medicine, 30 Medical Drive, Singapore 117609. 9 Department of Biochemistry, Yong Loo Lin School of Medicine, National University of 10 Singapore, Singapore 117597. 11 LKC School of Medicine, Nanyang Technological University, Singapore. 12
منابع مشابه
Inactivation of PPARβ/δ adversely affects satellite cells and reduces postnatal myogenesis.
Peroxisome proliferator-activated receptor β/δ (PPARβ/δ) is a ubiquitously expressed gene with higher levels observed in skeletal muscle. Recently, our laboratory showed (Bonala S, Lokireddy S, Arigela H, Teng S, Wahli W, Sharma M, McFarlane C, Kambadur R. J Biol Chem 287: 12935-12951, 2012) that PPARβ/δ modulates myostatin activity to induce myogenesis in skeletal muscle. In the present study,...
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تاریخ انتشار 2015